140 research outputs found

    ANOMALOUS MENTAL PHENOMENA RESEARCH IN RUSSIA AND THE FORMER SOVIET UNION: A FOLLOW UP

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    We describe our further exploration into research of anomalous mental phenomena (AMP) in the Former Soviet Union (FSU). We visited numerous research centers in major cities of Russia and the Ukraine, met with leading researchers in the field, visited their laboratories, and participated in some experiments. In their research, our Russian colleagues emphasize studies of anomalous perturbation (AP), also termed psychokinesis (PK), and "distant mental effect" on biological systems (bio-AP or bio-PK). The experiments have been conducted in top academic and research institutions, including Moscow State University, St. Petersburg State University, and several research institutes of the Russian and Ukrainian Academies of Sciences. Although the quality of research varies considerably in different institutions, there are groups that have developed rigorous methodologies. We also consider the potential cultural impact on Russian AMP research. We conclude with a discussion of the causal model of AP studies vs. informationaL perceptual model in relation to the Russian research

    OVERVIEW OF CURRENT PARAPSYCHOLOGY RESEARCH IN THE FORMER SOVIET UNION

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    This paper provides an in-depth discussion of research of anomalous mental phenomena (AMP) in the former Soviet Union. The authors spent approximately two months in Russia during 1992 and 1993, interacting with researchers in Moscow and Novosibirsk. The authors primarily discuss experiments in anomalous perturbation (often referred to as psychokinesis-PK and bioPK) which have been the main focus of AMP research programs in the Soviet Union. In particular, the authors discuss the methodologies and results of experimental attempts by human operators to affect the following inanimate and animate target systems: (1) microcalorimeters, (2) electric noise generators, (3) cellular cultures, (4) plant seeds, (5) plant biopotentials, (6) frequency of impulses emitted by an electricity-generating fish, (7) eating behavior of mice, (8) person's reaction time, and (9) parameters of human EEG

    OVERVIEW OF CURRENT PARAPSYCHOLOGY RESEARCH IN THE FORMER SOVIET UNION

    Get PDF
    This paper provides an in-depth discussion of research of anomalous mental phenomena (AMP) in the former Soviet Union. The authors spent approximately two months in Russia during 1992 and 1993, interacting with researchers in Moscow and Novosibirsk. The authors primarily discuss experiments in anomalous perturbation (often referred to as psychokinesis-PK and bioPK) which have been the main focus of AMP research programs in the Soviet Union. In particular, the authors discuss the methodologies and results of experimental attempts by human operators to affect the following inanimate and animate target systems: (1) microcalorimeters, (2) electric noise generators, (3) cellular cultures, (4) plant seeds, (5) plant biopotentials, (6) frequency of impulses emitted by an electricity-generating fish, (7) eating behavior of mice, (8) person's reaction time, and (9) parameters of human EEG

    The Design of a Best Execution Market

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    The notion of best execution on securities markets is manifold. Best execution has different meanings to different market participants, therefore, it is difficult to find a unique market structure that meets this requirements for all the participants. Traditional market structures are either static or flexible, meaning that an individual market participant has no influence regarding the concrete market structure’s characteristics, like e. g. the price discovery mechanism, trading frequency or the market transparency. Traditional market structures are either static or flexible, meaning that an individual market participant has no influence regarding the Focussing on customer orientation, we propose a new type of market structure: the dynamic market model, where participants individually choose the characteristics of the market structure for each transaction they perform. Furthermore, this paper offers an approach to design dynamic market models from scratch. We briefly sketch the necessary steps towards a dynamic market model. Traditional market structures are either static or flexible, meaning that an individual market participant has no influence regarding the Finally, we present AMTRAS; the prototype of an electronic trading system that was conceived and implemented following the aforementioned approach. AMTRAS is an software-agent based bond trading system designed for the need of institutional investors. It implements a dynamic market model, a sophisticated product- and partner matching scheme as well as an innovative price discovery approach

    Maintenance treatment with quetiapine versus discontinuation after one year of treatment in patients with remitted first episode psychosis: randomised controlled trial

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    Objective To study rates of relapse in remitted patients with first episode psychosis who either continued or discontinued antipsychotic drugs after at least one year of maintenance treatment

    Recommendations for reporting ion mobility mass spectrometry measurements

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    © 2019 The Authors. Mass Spectrometry Reviews Published by Wiley Periodicals, Inc. Here we present a guide to ion mobility mass spectrometry experiments, which covers both linear and nonlinear methods: what is measured, how the measurements are done, and how to report the results, including the uncertainties of mobility and collision cross section values. The guide aims to clarify some possibly confusing concepts, and the reporting recommendations should help researchers, authors and reviewers to contribute comprehensive reports, so that the ion mobility data can be reused more confidently. Starting from the concept of the definition of the measurand, we emphasize that (i) mobility values (K0) depend intrinsically on ion structure, the nature of the bath gas, temperature, and E/N; (ii) ion mobility does not measure molecular surfaces directly, but collision cross section (CCS) values are derived from mobility values using a physical model; (iii) methods relying on calibration are empirical (and thus may provide method-dependent results) only if the gas nature, temperature or E/N cannot match those of the primary method. Our analysis highlights the urgency of a community effort toward establishing primary standards and reference materials for ion mobility, and provides recommendations to do so. © 2019 The Authors. Mass Spectrometry Reviews Published by Wiley Periodicals, Inc

    Prediction of Locally Advanced Urothelial Carcinoma of the Bladder Using Clinical Parameters before Radical Cystectomy - A Prospective Multicenter Study

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    Introduction: We aimed at developing and validating a pre-cystectomy nomogram for the prediction of locally advanced urothelial carcinoma of the bladder (UCB) using clinicopathological parameters. Materials and Methods: Multicenter data from 337 patients who underwent radical cystectomy (RC) for UCB were prospectively collected and eligible for final analysis. Univariate and multivariate logistic regression models were applied to identify significant predictors of locally advanced tumor stage (pT3/4 and/or pN+) at RC. Internal validation was performed by bootstrapping. The decision curve analysis (DCA) was done to evaluate the clinical value. Results: The distribution of tumor stages pT3/4, pN+ and pT3/4 and/or pN+ at RC was 44.2, 27.6 and 50.4%, respectively. Age (odds ratio (OR) 0.980; p < 0.001), advanced clinical tumor stage (cT3 vs. cTa, cTis, cT1; OR 3.367; p < 0.001), presence of hydronephrosis (OR 1.844; p = 0.043) and advanced tumor stage T3 and/or N+ at CT imaging (OR 4.378; p < 0.001) were independent predictors for pT3/4 and/or pN+ tumor stage. The predictive accuracy of our nomogram for pT3/4 and/or pN+ at RC was 77.5%. DCA for predicting pT3/4 and/or pN+ at RC showed a clinical net benefit across all probability thresholds. Conclusion: We developed a nomogram for the prediction of locally advanced tumor stage pT3/4 and/or pN+ before RC using established clinicopathological parameters

    Empirical Legal Studies Before 1940: A Bibliographic Essay

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    The modern empirical legal studies movement has well-known antecedents in the law and society and law and economics traditions of the latter half of the 20th century. Less well known is the body of empirical research on legal phenomena from the period prior to World War II. This paper is an extensive bibliographic essay that surveys the English language empirical legal research from approximately 1940 and earlier. The essay is arranged around the themes in the research: criminal justice, civil justice (general studies of civil litigation, auto accident litigation and compensation, divorce, small claims, jurisdiction and procedure, civil juries), debt and bankruptcy, banking, appellate courts, legal needs, legal profession (including legal education), and judicial staffing and selection. Accompanying the essay is an extensive bibliography of research articles, books, and reports

    Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.

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    Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability
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